Discrete-event simulation of logistics and production systems plays an important role in the context of digital transformation. Its integration into modern planning and control processes is urgently required in order to realize Industry 4.0 concepts. In addition, simulation models will be an important part of the so-called digital twin in the planning and operation. However, the requirements for simulation models and tools are not yet comprehensively defined, and technical solutions have not been adequately implemented. This article presents the fields of action for the implementation.