Typeset

Customized Organs from Space

Customized Organs from Space

How weightlessness could change human lives
Due to its weightlessness, space offers enormous opportunities for production. The unique conditions of microgravity, for example, can simplify the development of organs and tissues from the body's own stem cells, allowing therapies to be developed in a more targeted manner. Even though many independent initiatives are currently emerging to explore this and other potential applications, their success is not a foregone conclusion.
I4S 5/2025: Artificial Intelligence and Digital Assistance

I4S 5/2025: Artificial Intelligence and Digital Assistance

How we can better support work
Demographic change, skills shortages, and stagnating productivity are threatening the competitiveness of German industry. At the same time, AI and digital assistance systems are opening up new opportunities: they make work more efficient and support skilled workers. But while they have long been part of everyday life, their potential in industry remains largely untapped—this is where this issue comes in with innovative concepts.
Bridging Knowledge Gaps with GenAI in Industrial Maintenance

Bridging Knowledge Gaps with GenAI in Industrial Maintenance

Specific needs and contextualized solutions
Uta Wilkens ORCID Icon, Julian Polte ORCID Icon, Philipp Lelidis, Eckart Uhlmann ORCID Icon
The paper specifies the genAI support needs for industrial maintenance against the background of a sociotechnical systems perspective. Emphasizing two needs, accessing implicit operator knowledge and prioritizing complex regulatory knowledge, a multi-layer architecture is outlined for an AI-based context-sensitive maintenance assistance system (MAS). The main purpose is to bridge knowledge gaps with genAI if human expertise and human implicit knowledge are not available and to cope with sub-process-specific challenges of multiple regulations. The MAS facilitates access to technical knowledge, distributes expertise, and shares implicit knowledge of experienced operators across different layers of information processing. The approach goes beyond standardization and has a high potential to enhance organizational as well as individual resilience.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 50-57 | DOI 10.30844/I4SE.25.5.50
The Bias of “Instructional Systems for the Disabled”

The Bias of “Instructional Systems for the Disabled”

Ethnographic insights from deploying augmented reality in a sheltered workshop
David Kostolani ORCID Icon, Annemarie Ploss, Sebastian Schlund ORCID Icon
The rehumanization of industrial work has emerged as a key focus in Industry 4.0 research, emphasizing the empowerment of human workers amidst advancing automation. Within this re-search, supporting workers with disabilities through digital assistance technologies serves as a prime example of a human-centric approach to industrial engineering. These technologies often claim to enhance productivity, which aims to promote the integration of workers with disabili-ties in industrial roles. But can they genuinely improve their work experience? This ethnograph-ic study presents insights from two years of developing and deploying augmented reality in a sheltered woodworking workshop. Over this period, we engaged in conversations and facilitat-ed over 30 technology sessions with workers with diverse disabilities. Our experiences chal-lenge the narrative of industrial research, in particular with digital instructional systems serving as “enabler technology” to help them work “better.” ...
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 102-110 | DOI 10.30844/I4SE.25.5.102
Applied Knowledge and Augmented Reality

Applied Knowledge and Augmented Reality

Bridging the gap between learning and application
Jana Gonnermann-Müller ORCID Icon, Philip Wotschack, Martin Krzywdzinski ORCID Icon, Norbert Gronau ORCID Icon
The increasing complexity of industrial environments demands new competencies from workers, particularly the ability to interact with advanced digital systems. Traditional training methods often fall short in supporting the effective transfer of applied knowledge to such contexts, and the effectiveness of this transfer, as measured by performance-based outcomes, remains to be investigated. To address this gap, the present study employed a between-subjects experimental design comparing augmented reality- and paper-based instructions within a realistic production training scenario. The results show that participants who learned with augmented reality completed the production process significantly faster and with fewer errors than those using paper instructions. In addition, learners using augmented reality reported higher usability and experienced lower cognitive load during training. These findings suggest that augmented reality can enhance the transfer of practical skills in industrial ...
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 22-29 | DOI 10.30844/I4SE.25.5.22
AI-Based Recommender Systems in Product Development

AI-Based Recommender Systems in Product Development

A framework for knowledge discovery from multimodal data in industrial applications
Sebastian Kreuter ORCID Icon, Philipp Besinger, Alexander Lichtenberg, Fazel Ansari, Wilfried Sihn
The engineer-to-order (ETO) production approach is gaining relevance in response to increasing demand for individualized products and small batch sizes. However, ETO inherently reduces the economies of scale typically achieved in series production, as each order requires tailored engineering and production steps. This loss of efficiency can be mitigated through demand-driven and context-aware information provision throughout the product development process. A recommendation system based on semantic artificial intelligence (AI) and machine learning can support this by i) analyzing historical data and prior knowledge, for example drawings or a bill of materials from previous projects, and ii) making automated suggestions, like reusing existing designs or proposing design alternatives, thus compensating for the aforementioned effects.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 94-101 | DOI 10.30844/I4SE.25.5.94
Towards Human-Centered Industrial AI Adoption

Towards Human-Centered Industrial AI Adoption

A reference architecture for machine vision demonstrators
Dominik Arnold ORCID Icon, Florian Bülow ORCID Icon, Bernd Kuhlenkötter ORCID Icon
Despite its potential, the introduction of artificial intelligence (AI) in industry is often delayed, primarily due to perceived complexity, high costs, and a lack of expertise. This article presents a modular demonstrator reference architecture that provides practical, low-cost access to industrial AI applications. Developed within a design science research approach, it specifically supports experimentation, learning, and gradual integration into existing production processes. The focus is on machine vision, implemented using cost-effective hardware and open-source software. Its applicability is demonstrated in three scenarios: quality control, chip classification, and in-company training. Initial evaluations confirm the technical feasibility, didactic relevance, and transferability to a variety of industrial contexts.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 152-160 | DOI 10.30844/I4SE.25.5.146
Biomechanical Simulation Pipeline for Exoskeletons

Biomechanical Simulation Pipeline for Exoskeletons

A digital tool for the targeted development of support systems
Robert Eberle ORCID Icon, Maximilian Ebenbichler ORCID Icon, Benjamin Reimeir ORCID Icon, Lennart Ralfs ORCID Icon, Robert Weidner ORCID Icon
Support systems like exoskeletons can reduce physical strain on workers in industrial workplaces. To facilitate their development, a simulation pipeline was created. This pipeline employs musculoskeletal human models coupled with an exoskeleton model, enabling detailed analyses of the biomechanical interaction between humans and exoskeletons. By implementing exoskeleton structures and integrating them into existing musculoskeletal models, the pipeline aims to optimize exoskeleton development while simultaneously enhancing their biomechanical effectiveness.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 30-36 | DOI 10.30844/I4SE.25.5.30
Frameworks for the Structural Integration of Artificial Intelligence

Frameworks for the Structural Integration of Artificial Intelligence

Comparing organizational approaches
Sascha Stowasser
Artificial intelligence is increasingly implemented in companies, but often without clear organizational anchoring. This article evaluates centralized, decentralized, hybrid, and project-based frameworks for the structural integration of artificial intelligence in corporate organizations. A decision table provides guidance for selecting suitable models. In the conclusion, further open research questions are posed.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 144-151 | DOI 10.30844/I4SE.25.5.138
Assistance for Simulation in Production and Logistics

Assistance for Simulation in Production and Logistics

A literature-based classification
Sigrid Wenzel ORCID Icon, Felix Özkul, Robin Sutherland ORCID Icon
Despite the commercial availability of simulation tools, using of discrete-event simulation for complex production and logistics systems is becoming increasingly challenging. It requires extensive expertise, high data quality, and considerable time and financial resources. For many years, therefore, there has been high demand for methodological and organizational support for the conduction of simulation studies. This article is based on an analysis of relevant publications and aims to classify previous research on improving the use of simulation. It also raises the question of the need for assistance in applying discrete event simulation and identifies areas for action.
Industry 4.0 Science | Volume 41 | 2025 | Edition 5 | Pages 66-76 | DOI 10.30844/I4SE.25.5.64
1 4 5 6 44