The research project “Open Innovation in Life Sciences” (project duration May 2008-April 2011) aims at the development and implementation of new innovation strategies and concepts for SMEs in the life sciences segment. In particular inside-out and outside-in processes in joint innovation projects beyond firm boundaries are analyzed. The life sciences segment is known as being highly research intense and interdisciplinary. As a result of the growing complexity of innovation processes, the development of cooperative, i.e. open innovation strategies for SMEs has become more important. SMEs can gain the capability to tap crucial innovation potentials by bundling distributed complementary knowledge. The article describes the development of a method which might help to evaluate opportunities and risks of different innovation concepts. This may serve as basis for decision-making regarding the implementation of a predefined innovation process. Project outcomes are expected to be an ...