Nowadays, the production of many goods takes place in distributed facilities within supply chains. The production planning of single facilities is based on due dates for delivery of raw materials or intermediate products that were agreed with supply chain partners. Thus, for an efficient overall system it is of major importance that these due dates are fulfilled. However, production systems are usually subjected to disruptions that put the execution of a given schedule at risk. This paper presents a method for the signal-based detection of faults in production systems. In addition to the fault detection, a heuristic method is employed that mitigates the disruptions and leads to a reliable production.