Changes on the product and manufacturing side resulting from intensifying global competition have put pressure on companies to alter their strategy, organization and production. Especially the ability to quickly adapt production equipment has become a crucial factor which can provide great competitive advantage. Current research work of the Institute for Manufacturing Automation and Production Systems (FAPS) at the University of Erlangen-Nürnberg focuses on material-flow and production systems that are both self-organizational and self-learning. In this context, concepts have been developed for cost-effective restructuring measures during the operating phase which make a rapid response to dynamic changes and disturbances possible.