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The design of inclusive work systems is gaining importance due to demographic change and the increasing digital penetration of value creation processes. While traditional ergonomic approaches are based primarily on percentile logic and thus address only a portion of the user population, the integration of digital technologies opens up new possibilities for the dynamic and individualized adaptation of work systems. This article presents a conceptual framework for inclusive work system design that integrates standardization, automation, and adaptability. Methodologically, the article is based on a conceptual analysis of existing approaches from ergonomics and human-centered design. The article makes a theoretical contribution to the systematization of inclusive work system design and identifies areas of focus for further research and industrial practice.