Cell disruption technologies used in industry and research are versatile and divided into biological, chemical and physical technologies. Physical technologies are subdivided into mechanical and non-mechanical. Common used cell disruption devices like the French Press does not enable a continuously cell disruption with a high amount of sample volumes. The text at hand describes a new continuously operating cell disruption device developed at Fraunhofer-Institute for Production Systems and Design Technology. Concluding the application possibilities and potentials are described.