Industry 4.0-related potentials leading to Industry 4.0 implementation mostly remain unclear. Consequently, this paper analyzes potentials that drive manufacturers to implement Industry 4.0 in five industries. Whereas mechanical and plant engineering as well as electrical engineering companies consider business-model driven, operational as well as ecological and social benefits as relevant for Industry 4.0 implementation, the chemical and steel industry widely disregard business-model driven opportunities. The automotive industry merely focuses on operational benefits provided by Industry 4.0.