The increased application of Cyber-Physical Systems (CPS) in production and manufacturing sector increases the demand on functional safety and reliability. Maintenance is responsible to ensure the availability of resources. In this context the question is, which Labour Organization and maintenance philosophy can be achieved in economic terms. It is important to know what type of four typical organization variants are to be preferred in short, medium and long term. The relative comparison is carried out taking into account different organization forms to the achievement of objectives. The selected set of objectives is taken into account for CPS typical effectiveness and efficiency dimensions.