The increasing number of copied products of increasing complexity as well as their increasing quality is presenting a challenging task to German industry. It is important to protect the own company of unwanted loss of know-how with appropriate input of resources. To solve this task, a number of possible measures exist. Their origin reaches from juridical measures like patents and brands and technological measures like labelling through holograms or similar items to organizational and strategic counter measures. The following paper presents a scientific approach to designing individual and comprehensive concepts for protection against unwanted loss of know-how and product piracy. The approach is evaluated in industry and includes necessary methods.