It is against the background of Industrie 4.0 that profound knowledge of the principles and basics of manual work or efficient work design, respectively, gains particular importance. It will continue to be a fair and neutral reference basis for the design of productive and ergonomic work in the Smart Factory. By collecting both time-relevant and ergonomically relevant data, MTM-HWD® (Human Work Design) a new MTM (Methods-Time Measurement) building block system offers an unprecedented quality in describing and evaluating human work. It, thus, combines work method-oriented with ergonomic work design.