Industry 4.0 is a political concept intended to help German manufacturing companies to exploit data potential. Today, maintenance activities are not proactive by current approaches. Decision support systems based on artificial intelligence allow a change here by even foresighted machine maintenance. However, AI’s opaque decision-making process represents a barrier for users, which endangers its effectiveness. Therefore, this article sheds light on both: the technological as well as social factor for the adoption of AI in Industry 4.0.