The information and communication technology distinguish the modern mechanical and automotive engineering. This is described by the term mechatronics. The development progress of information and communication technologies open up further fascinating perspectives: mechatronic systems with inherent partial intelligence. The term Self-optimization characterizes this perspective. Self-optimizing systems are able to react on changing environmental conditions and to optimize their behaviour autonomously. This contribution presents the paradigm of Self-optimization. The potential of Self-optimization is explained by two examples from the system RailCab.